Using clean fingertip, apply sparingly directly to breakout blemish or trouble spot. It is best to apply immediately upon detection to unbroken skin.
Typically, once-daily application at night is recommended, but may be applied twice a day or more on particularly active eruptions where excessive drying is not an issue. For those not experiencing continuous persistent acne, sometimes a single application to an un-inflamed pimple can encourage its resolve within a couple of days. In general, once tenderness has subsided, discontinue application and leave to heal naturally to avoid over-dryness to skin.